Best NFL Bets Week 2: Saints upset Buccaneers, Colts bounce back, Patrick Mahomes and Justin Herbert lead a shootout

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Sloan Piva

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Week 2 of the 2022 NFL season is here, and there are plenty of opportunities for bettors to find edges and angles. Here are the best bets for the full 16-game slate, including moneylines, spreads, over/unders, and props.
 
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